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Recombinant Human Leukocyte Mono Ig-Like Receptor 1/LMIR1/CD300a (C-Fc-6His)

Recombinant Human Leukocyte Mono Ig-Like Receptor 1/LMIR1/CD300a (C-Fc-6His)

Catalog Number:
P001411543ABE
Mfr. No.:
Abe32-9690
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      • Overview

        • CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.

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      • Properties
        • Protein Name
          CMRF35-like molecule 8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor
          Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 150mM NACl, 5% Trehalose, pH 8.0.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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