Name: Recombinant Human Interleukin-22/IL22 (C-6His)
Price: Inquiry

- Overview
  - Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF
    
    Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Interleukin-22/IL22 (C-6His)

Recombinant Human Interleukin-22/IL22 (C-6His)

We Also Recommend

Recombinant Human ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1/CD38 (C-Fc)

Recombinant Human Cell Death 1 Ligand 1/PD-L1/B7-H1/CD274 (C-His, variant)

Recombinant Human Tumor Necrosis Factor Ligand/TNFSF13/APRIL (N-Flag-His)