Name: Recombinant Human IKK alpha (N-GST tag)
Price: 672.00 USD

- Overview
  - IKKa is a serine/threonine protein kinase that phosphorylates the I-kappa-B protein which is an inhibitor of the transcription factor NF-kappa-B complex. Phosphorylation of I-kappa-B protein triggers the degradation of the inhibitor via the ubiquitination pathway, thereby activating NF-kappa-B complex. IKKa is an essential regulator of NF-kappa-B-dependent gene expression through control of promoter-associated histone phosphorylation after cytokine exposure. IKKa is a critical component of the cytoplasmic transductional-transcriptional processor leading to induction of IFNa production. IKKa is also involved in the epidermis where it antagonizes mitogenic and angiogenic signals and represses tumor progression and metastases.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    CHUK, IKK1, IKBKA, TCF16, NFKBIKA, IKK-alpha
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    114.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

Recombinant Human IKK alpha (N-GST tag)

Recombinant Human IKK alpha (N-GST tag)

We Also Recommend

Recombinant Human HIPK4 (N-GST tag)

Recombinant Human HPK1 (N-GST tag)

Recombinant Human HUNK (N-GST tag)