Name: Recombinant human HMG-1/HMGB1 protein , 1-215aa
Price: 279.00 USD

- Overview
  - Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Sulfoglucuronyl carbohydrate binding protein, SBP-1, HMGB1, HMG3, HMG1, High-mobility group box1, High-mobility group (nonhistone chromosomal) protein 1, DKFZp686A04236, Amphoterin
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    > 90% by SDS-PAGE
    
    Formulation
    
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM EDTA, 0.5mM DTT, 10% glycerol
    
    Storage
    
    Stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
    
    Concentration
    
    1mg/ml (determined by Bradford assay)
    
    Molecular Weight
    
    25 kDa (223aa) confirmed by MALDI-TOF
    
    Expression system
    
    Baculovirus
    
    More Information
    
    UniProt
    
    P09429
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application
    
    SDS-PAGE
- Reference
  - Min HJ, et al. Chaperone-like Activity of High-Mobility Group Box 1 Protein and Its Role in Reducing the Formation of Polyglutamine Aggregates. (J Immunol. 2013)
    Slean MM, et al. Interconverting Conformations of Slipped-DNA Junctions Formed by Trinucleotide Repeats Affect Repair Outcome. (Biochemistry. 2013)
    Takahashi T, et al. Bone-Targeting Endogenous Secretory Receptor for Advanced Glycation End Products Rescues Rheumatoid Arthritis. (Mol Med. 2013)
    Roy A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. (J Biol Chem. 2014)
    Sugimoto K, et al. Receptor for Advanced Glycation End Products - Membrane Type1 Matrix Metalloproteinase Axis Regulates Tissue Factor Expression via RhoA and Rac1 Activation in High-Mobility Group Box-1 Stimulated Endothelial Cells. (PLoS One. 2014)
    Hernández-Pando R, et al. The Role of High Mobility Group Box 1 Protein (HMGB1) in the Immunopathology of Experimental Pulmonary Tuberculosis. (PLoS One. 2015)
    Ito M, et al. High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats. (Metab Brain Dis. 2017)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Recombinant human HMG-1/HMGB1 protein , 1-215aa

Recombinant human HMG-1/HMGB1 protein , 1-215aa

More Information

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