Name: Recombinant Human High Mobility Group Protein B1/HMGB1 (N-MARI)
Price: Inquiry

- Overview
  - MW : 10kD. Recombinant Human High mobility group protein B1 is produced by our E.coli expression system and the target gene encoding Pro92-Val176 is expressed with a MARI tag at the N-terminus. High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
    
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- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of 50mM HEPES-Na, p H 7.9, 500mM NaCl, 0.6mM DTT.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P09429
    
    Gene ID
    
    3146
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human High Mobility Group Protein B1/HMGB1 (N-MARI)

Recombinant Human High Mobility Group Protein B1/HMGB1 (N-MARI)

More Information

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