Recombinant Human Heat Shock 70kDa protein 1B

Recombinant Human Heat Shock 70kDa protein 1B

Catalog Number:
P001414552ABE
Mfr. No.:
Abe32-5334
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • The HSPA1B Protein Human produced in E. Coli is a single, non-glycosylated polypeptide chain containing 650 amino acids having a molecular mass of 71.16kDa. HSPA1B is fused to a 10 amino acids His-Tag at N-terminus and purified by proprietary chromatographic techniques. The HSP70 family is found in many intracellular compartments such as chloroplasts, endoplasmic reticulum, mitochondria, and cytosol. These proteins are induced by a variation of biological stresses, including heat stress, in every organism. HSP70 has a range of functions. For example: HSP70 acts as molecular chaperones facilitating the assembly of multi-protein complexes, HSP70 take part in the translocation of polypeptides across cell membranes and to the nucleus, and HSP70 assists in the proper folding of nascent polypeptide chains. HSP70 is a mitochondrial import equipment and has a crucial part in the cytosolic endoplasmic reticulum. Lately, extracellular localized HSP was discovered to take an important part in the induction of a cellular immune response.

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      • Properties
        • Protein Name
          Heat shock 70kDa protein 1B, HSP70-2, HSP70-1/HSP70-2, FLJ54328, HSPA1A, heat shock 70kDa protein 1A/1B, HSPA1.
          Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          The protein was filtered (0.4µm) and lyophilized from a 0.5mg/ml solution containing 50mM phosphate buffer, 75mM NaCl, pH 7.4.
          Storage
          Lyophilized HSPA1B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSPA1B should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to add deionized water to prepare a working stock solution of 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

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