Recombinant Human GRK5 (N-GST tag)

Recombinant Human GRK5 (N-GST tag)

Catalog Number:
E001278346APP
Mfr. No.:
Z500157
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. GRK5 plays a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Desensitization of G protein-coupled receptors regulates the number of polymorphonuclear leukocytes (PMNs), as well as their motility and ability to stop upon contact with pathogens or target cells, and this desensitization is mediated by GRK5.

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      • Properties
        • Name
          GPRK5
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          95.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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