Login / Register
0

Recombinant Human GLK (N-GST tag)

Recombinant Human GLK (N-GST tag)

Catalog Number:
E001278350APP
Mfr. No.:
Z500153
Price:
$1,110
  • Size:
    10 µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • GLK is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain. GLK is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-? and can lead to the activation of the JNK signaling pathway. GLK can directly activate PKC-? during TCR signaling and people with systemic lupus erythematosus show considerable enhanced GLK expression and activation of PKC-? and the kinase IKK in T cells. GLK can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM.

          Please contact us at for specific academic pricing.

      • Properties
        • Name
          MAP4K3; MAPKKKK3; MEKKK3; RAB8IPL1
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          70.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

    We Also Recommend

    Recombinant Human FRK (N-GST tag)

    Recombinant Human FRK (N-GST tag)

    $672

    Recombinant Human FYN A (N-GST tag)

    Recombinant Human FYN A (N-GST tag)

    $672

    Recombinant Human GCK (N-GST tag)

    Recombinant Human GCK (N-GST tag)

    $672

    Note: If you don't receive our verification email, do the following:

    Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.