Name: Recombinant human FLT3 protein with C-terminal human Fc and 6×His tag
Price: Inquiry

- Overview
  - The protein has a predicted molecular mass of 125-130 kDa after removal of the signal peptide. Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Flt-3, Flk-2, STK-1, CD135, FLK2, FLT-3
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
    
    Formulation
    
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    
    Storage
    
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human FLT3, hFc-His Tag on SDS-PAGE under reducing condition.

Recombinant human FLT3 protein with C-terminal human Fc and 6×His tag

Recombinant human FLT3 protein with C-terminal human Fc and 6×His tag

We Also Recommend

CD4 (203-317) Recombinant Protein

Recombinant human CD47 protein with C-terminal mouse Fc and 6×His tag

Recombinant human SIRP alpha protein with C-terminal human Fc and 6×His tag