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Recombinant Human DYRK4 (N-GST tag)

Recombinant Human DYRK4 (N-GST tag)

Catalog Number:

E001278310APP

Mfr. No.:

Z500112

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - DYRK4 or dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 plays an important role in cell proliferation, survival, and development. Northern blot analysis shows DYRK4 is highly expressed in the testis with a very restricted expression to stage VIII postmeiotic spermatids. Analysis of a DYRK4 deficient mouse line showed that DYRK4 is dispensable for male fertility, hence suggesting a functional redundancy of some DYRK isoforms during spermiogenesis. DYRK4 protein contains a DYRK homology box in its N-terminal half, followed by a central kinase domain with a YxY loop.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    90.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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