Name: Recombinant Human Complement Factor H-related Protein 1/CFHR1(C-His)
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- Overview
  - Complement factor H-related protein 1 (CFHR1) is a secreted protein that is a member of the complement factor H protein family. CFHR1 is expressed by hepatocytes and exists as two differentially glycosylated isoforms. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. CFHR1 might mediate complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. A common CFHR1/CFHR3 genetic deletion has been recognized as being protective against age-related macular degeneration and nephropathy.
    
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- Properties
  - Protein Name
    
    Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 0.01%Tween 80, pH 7.4
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Complement Factor H-related Protein 1/CFHR1(C-His)

Recombinant Human Complement Factor H-related Protein 1/CFHR1(C-His)

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