Name: Recombinant Human CD40 Ligand/CD40L/TNFSF5
Price: Inquiry

- Overview
  - MW : 16.2kD. Recombinant Human TNFSF5 is produced by our Mammalian expression system and the target gene encoding Met113-Leu261 is expressed. CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of 20mM PB, 200mM NaCl, 0.1mM EDTA, pH 7.0.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P29965
    
    Gene ID
    
    959
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human CD40 Ligand/CD40L/TNFSF5

Recombinant Human CD40 Ligand/CD40L/TNFSF5

More Information

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