Recombinant Human CaM Kinase II Subunit beta/CAMK2B (C-6His)

Recombinant Human CaM Kinase II Subunit beta/CAMK2B (C-6His)

Catalog Number:
P001410997ABE
Mfr. No.:
Abe32-8171
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      • Overview
        • MW : 57.4kD. Recombinant Human CaM Kinase II Subunit Beta is produced by our E.coli expression system and the target gene encoding Met1-Gln503 is expressed with a 6His tag at the C-terminus. Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta (CAMK2B) is a cytoplasmic protein that belongs to the serine/threonine protein kinase family and the Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2B is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplamic reticulum Ca2+ transport in skeletal muscle. In neurons, CAMK2B plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 10mM HEPES, 150mM NaCl, pH 7.5.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          816

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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