Recombinant Human Bone Morphogenetic Protein 2/BMP-2

Recombinant Human Bone Morphogenetic Protein 2/BMP-2

Catalog Number:
P001414936ABE
Mfr. No.:
Abe32-7011
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      • Overview
        • MW : 13.3kD. Recombinant Human Bone Morphogenetic Protein 2 is produced by our E.coli expression system and the target gene encoding Gln283-Arg396 is expressed. Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of 50mM HAc .
          Storage
          Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          ED50 is less than 50 ng/ml. Specific Activity of 2.0 x 10^4 IU/mg

          More Information

          UniProt
          Gene ID
          650

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 50mM Acetic acid. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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