Recombinant FKBP52 Monoclonal Antibody

Recombinant FKBP52 Monoclonal Antibody

Catalog Number:
A001511444RED
Mfr. No.:
RD86942A
Price:
$392
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      • Overview
        • Calculated MW: 58kDa
          Observed MW: 58kDa

          Please contact us at for specific academic pricing.

          Background

          FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat; hamster
          Immunogen
          A synthetic peptide of human FKBP52
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          51 kDa FK506-binding protein, 52 kDa FK506 binding protein, 52 kDa FK506-binding protein, 52 kDa FKBP, 59 kDa immunophilin, FK506 binding protein 4, FK506-binding protein 4, FKBP 4, FKBP 52, FKBP 59, FKBP-4, FKBP-52, FKBP4, FKBP4, FKBP51, FKBP52 protein, FKBP59, HBI, Hsp 56, HSP binding immunophilin, HSP-binding immunophilin, Hsp56, Immunophilin FKBP52, N-terminally processed, p52, p59, p59 protein, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP4, Peptidylprolyl cis trans isomerase, PPIase, PPIase FKBP4, Rotamase, T cell FK506 binding protein 59kD (Gene ID:2288; UniProt:Q02790)

          * For reference only.

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:1000-1:5000
          IF 1:20-1:50

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