Name: RBP3 Polyclonal Antibody
Price: 237.00 USD

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  mouse; rat
  
  Immunogen
  
  Recombinant human Retinol-binding protein 3 protein
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  2 mg/mL
  
  Antigen
  
  D10S64, D10S65, D10S66, Interphotoreceptor retinoid binding protein, Interphotoreceptor retinoid-binding protein, Interstitial retinol binding protein, Interstitial retinol-binding protein, IRBP, RBP 3, rbp3, RBPI, RET3, Retinol binding protein 3, Retinol binding protein 3 interstitial, Retinol-binding protein 3, RP66 (UniProt:P10745)
  
  * For reference only.

Applications

Application

IHC

Application	Dilutions
IHC	1:50-1:100

RBP3 Polyclonal Antibody

RBP3 Polyclonal Antibody

Background

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