Rabbit anti-SOCS1 Polyclonal Antibody (0.89 mg/mL) for IHC

Rabbit anti-SOCS1 Polyclonal Antibody (0.89 mg/mL) for IHC

Catalog Number:
A001080243RED
Mfr. No.:
RD70446A
Price:
$347
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      • Overview
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          Background

          This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse; rat
          Immunogen
          KLH conjugated Synthetic peptide corresponding to Mouse SOCS1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.89 mg/mL
          Antigen
          CISH 1; CISH1; Cytokine inducible SH2 protein 1; JAB; JAK binding protein; JAK-binding protein; Janus kinase binding protein; SOCS 1; SOCS-1; Socs1; SOCS1; SSI 1; SSI-1; SSI1; STAT induced STAT inhibitor 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Supressor of cytokine signaling 1; TEC interacting protein 3; Tec-interacting protein 3; TIP 3; TIP-3; TIP3 (UniProt:O35716, Q9QX78)

          * For research use only.

      • Applications
        • Application
          IHC

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