Rabbit anti-S100B Polyclonal Antibody (0.54 mg/mL) for IHC

Rabbit anti-S100B Polyclonal Antibody (0.54 mg/mL) for IHC

Catalog Number:
A001080174RED
Mfr. No.:
RD70495A
Price:
$347
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      • Overview
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          Background

          S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new boimarker for mood disorders.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse; rat
          Immunogen
          KLH conjugated Synthetic peptide corresponding to Mouse S100B
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.54 mg/mL
          Antigen
          NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 protein beta chain; S100B; S100B; S100beta (UniProt:P50114, P04631)

          * For research use only.

      • Applications
        • Application
          IHC

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