Rabbit anti-RAE1 Polyclonal Antibody

Rabbit anti-RAE1 Polyclonal Antibody

Catalog Number:
A001084299RED
Mfr. No.:
RD84023A
Price:
$347
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      • Overview
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          Background

          Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human RAE1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          dJ481F12.3; dJ800J21.1; FLJ30608; Homolog of yeast Rae1 (Bharathi) mRNA associated protein of 41 kDa (Kraemer); Homolog of yeast Rae1 mRNA associated protein of 41 kDa; MGC117333; MGC126076; MGC126077; MIG 14; MIG14; Migration inducing gene 14; Mnrp 41; Mnrp41; mRNA associated protein mrnp 41; mRNA binding protein 41 kD; mRNA export factor; mRNA export protein; mRNA-associated protein mrnp 41; MRNP 41; MRNP41; RAE 1; RAE1 (RNA export 1 S.pombe) homolog; rae1; RAE1 homolog; Rae1 protein homolog; RAE1 RNA export 1 homolog (S. pombe); RAE1 RNA export 1 homolog; RAE1L; RNA export 1; RNA export 1 homolog (Gene ID:8480; UniProt:P78406)

          * For research use only.

      • Applications
        • Application
          WB; IHC; IF

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