Rabbit anti-QARS Polyclonal Antibody

Rabbit anti-QARS Polyclonal Antibody

Catalog Number:
A001084539RED
Mfr. No.:
RD84177A
Price:
$347
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant protein of human QARS
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          GlnRS; Glutamine tRNA ligase; Glutamine tRNA synthetase; Glutamine--tRNA ligase; Glutaminyl tRNA ligase; Glutaminyl tRNA synthetase; Glutaminyl-tRNA synthetase; PRO2195; QARS; SYQ (Gene ID:5859; UniProt:P47897)

          * For research use only.

      • Applications
        • Application
          WB; IHC; IF

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