Rabbit anti-PERK Polyclonal Antibody (1.4 mg/mL) for IHC

Rabbit anti-PERK Polyclonal Antibody (1.4 mg/mL) for IHC

Catalog Number:
A001080156RED
Mfr. No.:
RD70557A
Price:
$347
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      • Overview
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          Background

          The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          KLH conjugated Synthetic peptide corresponding to Human PERK
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1.4 mg/mL
          Antigen
          DKFZp781H1925; E2AK3; EC 2.7.11.1; Eif2ak3; Eukaryotic translation initiation factor 2 alpha kinase 3; Eukaryotic translation initiation factor 2-alpha kinase 3; Heme regulated EIF2 alpha kinase; HRI; HsPEK; Pancreatic eIF2 alpha kinase; Pancreatic eIF2-alpha kinase; PEK; PRKR like endoplasmic reticulum kinase; PRKR-like endoplasmic reticulum kinase; WRS (UniProt:Q9NZJ5)

          * For research use only.

      • Applications
        • Application
          IHC

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