Rabbit anti-NRGN Polyclonal Antibody

Rabbit anti-NRGN Polyclonal Antibody

Catalog Number:
A001085299RED
Mfr. No.:
RD85103A
Price:
$347
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      • Overview
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          Background

          Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human NRGN
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/ml
          Antigen
          Protein kinase C substrate RC3; Calmodulin binding protein; Hng; NEUG(55-78); NEUG; Neurogranin (protein kinase C substrate); Ng; NRGN; Protein kinase C substrate; RC3 (Gene ID:4900; UniProt:Q92686)

          * For research use only.

      • Applications
        • Application
          WB

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