Rabbit anti-NOD2 Polyclonal Antibody

Rabbit anti-NOD2 Polyclonal Antibody

Catalog Number:
A001075490RED
Mfr. No.:
RD76743A
Price:
$253
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      • Overview
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          Background

          This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human NOD2
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.8mg/mL
          Antigen
          ACUG; Arthrocutaneouveal granulomatosis; BLAU; CARD15; Caspase recruitment domain family; member 15; Caspase recruitment domain protein 15; Caspase recruitment domain-containing protein 15; CD; CLR16.3; IBD1; Inflammatory bowel disease protein 1; LRR containing protein; NLR family; CARD domain containing 2; NLRC2; NOD like receptor C2; NOD2; NOD2 protein; NOD2; NOD2B; nucleotide binding oligomerization domain 2; Nucleotide binding oligomerization domain containing 2; Nucleotide binding oligomerization domain; leucine rich repeat and CARD domain containing 2; Nucleotide-binding oligomerization domain-containing protein 2; PSORAS1 (UniProt:Q9HC29)

          * For research use only.

      • Applications
        • Application
          IHC; ELISA

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