Name: Rabbit anti-NLRP4 Polyclonal Antibody (0.5mg/mL) for IHC, ELISA
Price: 253.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human
    
    Immunogen
    
    Synthetic peptide of human NLRP4
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    0.5mg/mL
    
    Antigen
    
    Cancer/testis antigen 58; CLR19.5; CT58; FLJ32126; NACHT; leucine rich repeat and PYD containing 4; NACHT; LRR and PYD containing protein 4; NACHT; LRR and PYD domains-containing protein 4; NALP4; NLR family; pyrin domain containing 4; NLRP4; Nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 4; PAAD and NACHT containing protein 2; PAAD and NACHT-containing protein 2; PAN2; PYPAF4; PYRIN and NACHT-containing protein 2; PYRIN containing APAF1 like protein 4; PYRIN-containing APAF1-like protein 4; Ribonuclease inhibitor 2; RNH2 (UniProt:Q96MN2)
    
    * For research use only.
- Applications
  - Application
    
    IHC; ELISA