Rabbit anti-NFKBID Polyclonal Antibody

Rabbit anti-NFKBID Polyclonal Antibody

Catalog Number:
A001076222RED
Mfr. No.:
RD77278A
Price:
$253
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      • Overview
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          Background

          May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant protein of human NFKBID
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% sodium azide, 50% glycerol, PH7.3
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          0.4mg/mL
          Antigen
          I-kappa-B-delta; IkappaBdelta; IkappaBNS; IkB-delta; IKBD; IKBNS; NF-kappa-B inhibitor delta; NFKBID; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta; T-cell activation NFKB-like protein; TA-NFKBH (UniProt:Q8NI38)

          * For research use only.

      • Applications
        • Application
          WB; IHC; ELISA

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