Rabbit anti-Mineralocorticoid receptor Polyclonal Antibody (1.3 mg/mL) for WB

Rabbit anti-Mineralocorticoid receptor Polyclonal Antibody (1.3 mg/mL) for WB

Catalog Number:
A001080217RED
Mfr. No.:
RD70461A
Price:
$347
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      • Overview
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          Background

          This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1.3 mg/mL
          Antigen
          Aldosterone receptor; MCR; MGC133092; Mineralocorticoid receptor; MLR; MR; NR3 C2; NR3C2; NR3C2 protein; Nuclear receptor subfamily 3 group C member 2 (UniProt:P08235)

          * For research use only.

      • Applications
        • Application
          WB

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