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Overview
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Background
CXCR7 (C-X-C chemokine receptor type 7),also known as RDC1,is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity,and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression.
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- Properties
- Applications
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Overview