Name: Rabbit anti-AIFM1 Polyclonal Antibody (0.98 mg/mL) for IHC
Price: 347.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
- Properties
  - Host
    
    rabbit
    
    Antibody Type
    
    polyclonal
    
    Isotype
    
    IgG
    
    Reactivity
    
    human; mouse; rat
    
    Immunogen
    
    KLH conjugated Synthetic peptide corresponding to Mouse AIF
    
    Purification
    
    Affinity purification
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    
    Storage
    
    Store at -20°C. Avoid repeated freeze / thaw cycles.
    
    Concentration
    
    0.98 mg/mL
    
    Antigen
    
    AIFM1; AIFM1; Apoptosis inducing factor 1; mitochondrial; Apoptosis inducing factor; Apoptosis inducing factor; mitochondrion associated; 1; Apoptosis-inducing factor 1; CMTX4; COWCK; COXPD6; Harlequin; Hq; mAIF; MGC111425; MGC5706; mitochondrial; Neuropathy; axonal motor-sensory; with deafness and mental retardation; neuropathy; axonal; motor-sensory with deafness and mental retardation (Cowchock syndrome); PDCD 8; PDCD8; Programmed cell death 8 (apoptosis inducing factor); Programmed cell death 8; Programmed cell death 8 isoform 1; Programmed cell death 8 isoform 2; Programmed cell death 8 isoform 3; Programmed cell death protein 8; Programmed cell death protein 8 mitochondrial; Programmed cell death protein 8 mitochondrial precursor; Programmed cell death protein 8 mitochondrial precursor; Striatal apoptosis inducing factor (UniProt:O95831, Q9Z0X1, Q9JM53)
    
    * For research use only.
- Applications
  - Application
    
    IHC

Rabbit anti-AIFM1 Polyclonal Antibody (0.98 mg/mL) for IHC

Rabbit anti-AIFM1 Polyclonal Antibody (0.98 mg/mL) for IHC

Background

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