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Overview
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QTRTD1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 438 amino acids (1-415 a.a) and having a molecular mass of 49.1kDa. QTRTD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Queuine TRNA-Ribosyltransferase Domain Containing 1, also known asQTRTD1 act together with QTRT1 to form an active queuinetRNA-ribosyltransferase. QTRTD1 exchanges queuine for the guanine at the wobbleposition of tRNAs along with GUN anticodons (tRNA-Asp,-Asn,-His and -Tyr), inthat way forming the hypermodified nucleoside queuosine.
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- Properties
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Overview