Purified Anti-Mouse CD90.2 Monoclonal Antibody

Purified Anti-Mouse CD90.2 Monoclonal Antibody

Catalog Number:
A001087034RED
Mfr. No.:
RD21081F
Price:
$176
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      • Overview
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          Background

          CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2b kappa
          Reactivity
          mouse
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% Proclin300
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          Thy-1.2 membrane glycoprotein; Thy1.2; Thy-1.2 antigen; CD90.2; Thy-1.2 (Gene ID:21838; UniProt:P01831)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry; IHC

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