PURE - anti Human CD42b - HIP1

PURE - anti Human CD42b - HIP1

Catalog Number:
A001109132IMM
Mfr. No.:
42BPU-01MG
Price:
$361
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • This antibody reacts with the CD42b-antigen. It reacts with a two chain membrane glycoprotein, GpIb, that forms a non covalent complex with GPIX (CD42a) found on platelets and magakaryocytes. Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation. The GPIb/IX complex serves as the vWF surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls.

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      • Properties
        • Isotype
          IgG1
          Reactivity
          human
          Clone
          HIP1
          Immunogen
          Tissue / cell preparation (Human). Peripheral blood mononuclear cells of a patient suffering with CLL.
          Conjugate
          PURE
          Concentration
          Please refer to the Certificate of Analysis for the lot-specific concentration.
          Molecular Weight
          17-22kDa
          Regulatory Status
          RUO
          Antigen
          Glycocalicin, gpIbα (Gene ID:2812)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry
          Application Description
          CD42b, clone HIP1 is a mAb intended for the identification/enumeration of platelets, thrombocytes and megakaryocytes using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
      • Reference

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