PURE - anti Human CD146 - TEA1/34

PURE - anti Human CD146 - TEA1/34

Catalog Number:
A001109352IMM
Mfr. No.:
146PU-01MG
Price:
$363
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • This antibody reacts with the CD146 antigen, which is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified. Among peripheral whole blood leucocytes, CD146 expression is not detected, except on a subset of activated T-lymphocytes.

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      • Properties
        • Isotype
          IgG2a
          Reactivity
          human
          Clone
          TEA1/34
          Immunogen
          Human endothelial cells
          HUVECs
          Conjugate
          PURE
          Concentration
          Please refer to the Certificate of Analysis for the lot-specific concentration.
          Molecular Weight
          118 KDa
          Regulatory Status
          RUO
          Antigen
          S-Endo, Cell surface glycoprotein MUC18 (Gene ID:4162)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry
          Application Description
          CD146, clone TEA1/34 is a mAb intended for the identification of MUC18/MCAM antigen, an activation antigen of human T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.

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