PTPA Polyclonal Antibody (1.08 mg/mL) for IHC, ELISA

PTPA Polyclonal Antibody (1.08 mg/mL) for IHC, ELISA

Catalog Number:
A001508617RED
Mfr. No.:
RD253148A
Price:
$253
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      • Overview
        • Gene Accession: BC002545

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          Background

          Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Fusion protein of human PTPA
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.08 mg/mL
          Antigen
          subunit B'', KIAA0044 , MGC2184 , Phosphotyrosyl phosphatase activator, PP2A, PP2A phosphatase activator , PP2A subunit B', PP2A subunit B' isoform PR53, PP2A subunit B' PR53 isoform , PPP2R4, PR53 , PR53 isoform, Protein phosphatase 2, regulatory subunit B-prime, Protein phosphatase 2A activator regulatory subunit 4, Protein phosphatase 2A regulatory subunit B' (PR 53), PTPA, PTPA, Serine/threonine protein phosphatase 2A regulatory subunit B' , Serine/threonine-protein phosphatase 2A activator, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B'' (UniProt:Q15257)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:200
          ELISA 1:5000-1:10000

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