Name: pS594/pT597/pS599-SMO ( phospho-SMO Receptor Polyclonal Antibody )
Price: 528.00 USD

Overview
- Serine594/Threonine597/Serine599 (S594/S597/S599) is major GRK2 phosphorylation site of the SMO receptor. The pS594/pT597/pS599-SMO antibody detects phosphorylation in response to agonists. The pS594/pT597/pS599-SMO antibody can be used for detection of the subcellular location of phosphorylated SMO by immunocytochemistry.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic phosphopeptide derived from mouse SMO around the phosphorylation site of Ser594/Thr597/Ser599.
  
  Purification
  
  Antigen affinity chromatography
  
  Formulation
  
  Liquid
  
  Storage
  
  Short-term storage at 4°C and long-term storage at -20°C
  
  Antigen
  
  SMOH | FZD11 | frizzled family member 11 | bnb | smoothened, frizzled class receptor | smoothened (UniProt:Q99835 (human), P56726 (mouse), P97698 (rat))
  
  * This product is intended for research use only.

Applications

Application	Dilutions
Western Blot (WB)	1:1000
Immunocytochemistry (ICC)	1:1000

Reference
- Walker MF, Zhang J, Steiner W, Ku PI, Zhu JF, Michaelson Z, Yen YC, Long AB, Casey MJ, Poddar A, Nelson IB, Arveseth CD, Nagel F, Clough R, LaPotin S, Kwan KM, Schulz S, Stewart RA, Tesmer JJG, Caspary T, Subramanian R, Ge X, Myers BR. A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction. bioRxiv. 2023 May 11:2023.05.10.540226. doi: 10.1101/2023.05.10.540226. PMID: 37214942; PMCID: PMC10197709.

pS594/pT597/pS599-SMO ( phospho-SMO Receptor Polyclonal Antibody )