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Overview
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Serine372/Serine373 (S372/S373) is a major phosphorylation site of the D1 receptor. The pS372/pS373-D1 antibody detects phosphorylation in response to high- and low-efficacy agonists but not after PKC activation. S372/S373 phosphorylation is a key regulator of D1 desensitization, β-arrestin recruitment and internalization.
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