pS338/pS339-CXCR4 ( phospho-CXC Chemokine Receptor 4 Polyclonal Antibody )

Overview
- Serine338 and Serine339 (S338/S339) are a major phosphorylation sites of the CXCR4 receptor. The pS338/pS339-CXCR4 antibody detects phosphorylation in response to agonists and after PKC activation. S338/S339 phosphorylation is a key regulator of CXCR4 desensitization, β-arrestin recruitment and internalization.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser338/Ser339.
  
  Purification
  
  Antigen affinity chromatography
  
  Formulation
  
  Liquid
  
  Storage
  
  Short-term storage at 4°C and long-term storage at -20°C
  
  Antigen
  
  CXCR4, CXC Chemokine Receptor 4 (UniProt:P61073 (human), P70658 (mouse))
  
  * This product is intended for research use only.

Applications

Application	Dilutions
Western Blot (WB)	1:1000