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Overview
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Serine336/Serine337 (S336/S337) is a major phosphorylation site of the CCR5 receptor. The pS336/pS337-CCR5 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. S336/S337 phosphorylation is a key regulator of CCR5 desensitization, β-arrestin recruitment and internalization.
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