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Overview
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Serine332/serine334 (S332/S334) is a major phosphorylation site of the C5a1 receptor. The pS332/pS334-C5a1 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. S332/S334 phosphorylation is a key regulator of C5a1 desensitization, β-arrestin recruitment and internalization.
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