Login / Register

0

Figure 1. Agonist-induced Serine330 phosphorylation of the CXC Chemokine Receptor 4. HEK293 cells transiently expressing CXCR4 were either not exposed or exposed to 100 nM CXCL12 for 5 minutes. Cells were lysed and immunoblotted with the anti-pS330 antibody (7TM0071C) at a dilution of 1:1000 (upper panel). The same lysates were probed with the non-phospho-CXCR4 antibody (7TM0071N) at a dilution of 1:1000 (lower panel).

Figure 2. Agonist-induced Serine330 phosphorylation of the CXC Chemokine Receptor 4. Flp-In Trex 293 cells induced to express the CXCR4 were either not exposed or exposed to 100 nM CXCL12 for 5 minutes. Cells were lysed and immunoblotted with the anti-pS330 antibody (7TM0071C) at a dilution of 1:1000 (upper panel). The same lysates were probed with the non-phospho-CXCR4 antibody (7TM0071N) at a dilution of 1:1000 (lower panel).

pS330-CXCR4 ( phospho-CXC Chemokine Receptor 4 Polyclonal Antibody )

pS330-CXCR4 ( phospho-CXC Chemokine Receptor 4 Polyclonal Antibody )

Catalog Number:

A001455904TMA

Mfr. No.:

7TM0071C

Price:

$528

Size:

100 µl

Quantity:

Add to Cart:

Overview
- Serine330(S330) is a major phosphorylation site of the CXCR4 receptor. The pS330-CXCR4 antibody detects phosphorylation in response to agonists and after PKC activation. S330 phosphorylation is a key regulator of CXCR4 desensitization, β-arrestin recruitment and internalization.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser330.
  
  Purification
  
  Antigen affinity chromatography
  
  Formulation
  
  Liquid
  
  Storage
  
  Short-term storage at 4°C and long-term storage at -20°C
  
  Antigen
  
  CXCR4, CXC Chemokine Receptor 4 (UniProt:P61073 (human), P70658 (mouse))
  
  * This product is intended for research use only.

Applications

Application

WB

Application	Dilutions
Western Blot (WB)	1:1000

Note: If you don't receive our verification email, do the following:

Confirm that you entered your email address correctly.
Check if the email is in your spam or junk folder.
Or you may contact us at .

Products

Amerigo Scientific

Support

Contact Us

Copyright © Amerigo Scientific. All rights reserved.