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Overview
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Serine323 (S323) is a major phosphorylation site of the P2Y12 receptor. The pS323-P2Y12 antibody detects phosphorylation in response to high- and low-efficacy agonists and after PKC activation. S323 phosphorylation is a key regulator of P2Y12 desensitization, β-arrestin recruitment and internalization.
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