PP2A alpha Rabbit Polyclonal Antibody

PP2A alpha Rabbit Polyclonal Antibody

Catalog Number:
A001452132ZEN
Mfr. No.:
Zen-251610
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          The antiserum was produced against synthesized peptide derived from human PP2A-alpha.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 36 kDa; Observed MW: 36 kDa
          Antigen
          (Gene ID:5515; UniProt:P67775)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-F; IHC-P; ICC/IF; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100
          IF 1/50-1/200
          ELISA 1/10000

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