Name: Platelet factor-4 Native Protein
Price: Inquiry

- Overview
  - Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.
    
    Source
    
    Human platelets
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    
    Formulation
    
    The CXCL4 protein was lyophilized in PBS buffer pH-7.4.
    
    Storage
    
    Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Platelet factor-4 Native Protein

Platelet factor-4 Native Protein

We Also Recommend

PF 4 Recombinant Protein

PF 4 Variant-1 Recombinant Protein

PF4 His Recombinant Protein