Phospho-IRS1 (Ser636) Rabbit Polyclonal Antibody

Phospho-IRS1 (Ser636) Rabbit Polyclonal Antibody

Catalog Number:
A001451027ZEN
Mfr. No.:
Zen-251484
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 132 kDa; Observed MW: 150 kDa
          Antigen
          (Gene ID:3667; UniProt:P35568)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-F; IHC-P; ICC/IF; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100
          IF 1/50-1/200
          ELISA 1/10000

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