Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody

Catalog Number:
A001450926ZEN
Mfr. No.:
Zen-310312
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human HDAC6
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 131 kDa; Observed MW: 131 kDa
          Antigen
          (Gene ID:10013; UniProt:Q9UBN7)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1/500-1/1000

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