Phospho-CDC25A (Tyr59) Rabbit Polyclonal Antibody

Phospho-CDC25A (Tyr59) Rabbit Polyclonal Antibody

Catalog Number:
A001449696ZEN
Mfr. No.:
Zen-310263
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human CDC25A
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 59 kDa; Observed MW: 59 kDa
          Antigen
          (Gene ID:993; UniProt:P30304)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100

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