PHKA2 Polyclonal Antibody

PHKA2 Polyclonal Antibody

Catalog Number:
A001514381RED
Mfr. No.:
RD89999A
Price:
$416
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      • Overview
        • Calculated MW: 51kDa
          Observed MW: 55kDa

          Please contact us at for specific academic pricing.

          Background

          Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Recombinant fusion protein of human PHKA2
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          PHKA2, GSD9A, PHK, PYK, PYKL, XLG, XLG2 (Gene ID:5256; UniProt:P46019)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:2000

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