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Overview
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PF4V1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (31-104 a.a.) and having a molecular mass of 10.6kDa. PF4V1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Platelet Factor 4 Variant 1 (PF4V1) is a member of the intercrine alpha (chemokine CxC) family. PF4V1 is an inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis (in vitro). PF4V1 binding to heparin is much weaker than in the close homolog PF4/CXCL4.
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Overview