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Overview
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This antibody reacts with the intracellular enzyme, myeloperoxidase in peripheral blood granulocytes on cytospots in a characteristic granular pattern. Monocytes are negative or slightly positive while eosinophils and lymphocytes are negative. MPO antibodies stain promyelocytes, myelocytes, metamyelocytes and mature neutrophil granulocytes in bone marrow.
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