PE/Cyanine5 Anti-Human CD193/CCR3 Antibody [5E8]

PE/Cyanine5 Anti-Human CD193/CCR3 Antibody [5E8]

Catalog Number:
A001514985RED
Mfr. No.:
RD30678F
Price:
$307
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+?hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

      • Properties
        • Host
          mouse
          Isotype
          IgG2b kappa
          Reactivity
          human
          Conjugate
          PE/Cyanine5
          Formulation
          Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
          Storage
          This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
          Concentration
          5 μL/Test
          Antigen
          CC CKR3, MIP1-alpha receptor like-2, eotaxin receptor, CCR, C-C chemokine receptor type 3, (Gene ID:1232)

          * For reference only.

      • Applications
        • Application
          FCM

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