PE/AF594 Anti-Human CD45RO Antibody

PE/AF594 Anti-Human CD45RO Antibody

Catalog Number:
A001510382RED
Mfr. No.:
RD30316F
Price:
$209
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      • Overview
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          Background

          CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG2a kappa
          Reactivity
          human
          Conjugate
          PE/AF594
          Formulation
          PBS with 0.05% Proclin300, 1% BSA
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Antigen
          (Gene ID:5788)

          * For reference only.

      • Applications
        • Application
          FCM

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